Combiclav Injection
Combiclav injection is a broad spectrum antimicrobial solution for injection containing amoxicillin and clavulanic acid, indicated for the treatment of respiratory infections, soft tissue infections (e.g. joint/navel ill, abscesses etc.), metritis and mastitis. In the situation where systemic treatment as well as intramammary treatment is necessary, Combiclav Injection can be administered in combination with Combiclav Lactating Cow Intramammary Suspension.
Target Species: Beef cattle, dairy cattle
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Active Ingredient
Each ml contains: Amoxicillin (as Amoxicillin trihydrate) 14.0% Clavulanic acid (as Potassium clavulanate) 3.5%
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Pharmaceutical Form
Suspension for injection. An off-white to cream oily suspension
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Indications
Combiclav Injection has a notably broad spectrum of bactericidal activity against the bacteria commonly found in cattle. (a) In vitro Combiclav Injection is active against a wide range of clinically important bacteria including: Gram-positive: Staphylococci (including beta-lactamase producing strains), Streptococci, Corynebacteria, Clostridia, Bacillus anthracis, Actinomyces bovis. Gram-negative: Escherichia coli (including beta-lactamase producing strains), Salmonella spp (including beta-lactamase producing strains), Campylobacter spp, Klebsiella spp, Proteus spp, Pasteurella spp, Fusobacterium necrophorum, Bacteroides (including beta-lactamase producing strains), Haemophilus spp, Moraxella spp and Actinobacillus lignieresi. (b) Clinically Combiclav Injection is effective in treating: Cattle: Respiratory infections Soft tissue infections (e.g. joint/navel ill, abscesses etc.) Metritis Mastitis. Combined Therapy for the treatment of bovine mastitis. In the situation where systemic treatment as well as intramammary treatment is necessary, Combiclav Injection can be administered in combination with Combiclav Lactating Cow Intramammary Suspension.
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Dosage
For intramuscular injection at a dosage rate of 8.75 mg/kg bodyweight (1 ml per 20 kg bodyweight) daily for 3-5 days. Shake the vial well before use. After injection, massage the injection site. Use a completely dry sterile needle and syringe. Swab the septum before removing each dose. For Combined therapy the following minimum treatment regime should be followed:
To ensure the correct dosage, bodyweight should be determined as accurately as possible to avoid under dosing.
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