Combiclav Lactating Cow

Intramammary suspension. An off white to cream suspension

Combiclav Lactating Cow Intramammary Suspension is specially formulated for the treatment of bovine mastitis. It has a notably broad spectrum of bactericidal activity against the bacteria commonly isolated from the bovine udder. The prednisolone in Combiclav Lactating Cow Intramammary Suspension has an anti-inflammatory action which helps to reduce the potentially destructive swelling and inflammation associated with mastitis, without affecting the white cell response to infection. (i) In vitro Combiclav Lactating Cow Intramammary Suspension is active against a wide range of clinically important bacteria, including the following organisms, which are commonly associated with bovine mastitis: Staphylococci (including beta-lactamase producing strains). Streptococci (including S. agalactiae, S. dysgalactiae and S. uberis). A. pyogenes and other minor members of the Corynebacteria spp. Escherichia coli (including beta-lactamase producing strains). In addition, it is active in vitro against many less common udder pathogens including: Bacillus cereus, Bacteroides (including beta-lactamase producing strains), Campylobacter spp, Klebsiellae and Pasteurellae. (ii) Clinically, Combiclav Lactating Cow Intramammary Suspension has been shown to be an effective, routine treatment for mastitis in lactating cows. Cases responding successfully to treatment include infections with the following major pathogens: Staphylococci (including beta-lactamase producing strains). Streptococci (including S. agalactiae, S. dysgalactiae and S. uberis). Escherichia coli (including beta-lactamase producing strains). Combined Therapy for the treatment of bovine mastitis. In the situation where systemic treatment as well as intramammary treatment is necessary, Combiclav Injection can be administered in combination with Combiclav Lactating Cow Intramammary Suspension.

Combiclav Lactating Cow Intramammary Suspension is suitable for intramammary administration to lactating cattle at a dose rate of 3 syringes per affected quarter administered singly at 12 hour intervals. Use each syringe only once. After milking, clean and disinfect the teat end thoroughly with surgical spirit. Insert the syringe nozzle into the teat orifice and apply gentle and continuous pressure until the suspension is expressed. The treated quarter(s) may be milked out at the next normal milking time, but the milk should be discarded. For Combined therapy the following minimum treatment regime should be followed: